منابع مشابه
Perioperative organ injury.
Despite the fact that a surgical procedure may have been performed for the appropriate indication and in a technically perfect manner, patients are threatened by perioperative organ injury. For example, stroke, myocardial infarction, acute respiratory distress syndrome, acute kidney injury, or acute gut injury are among the most common causes for morbidity and mortality in surgical patients. In...
متن کاملPerioperative acute kidney injury.
Perioperative acute kidney injury (AKI) is not uncommon and is associated with considerable morbidity and mortality. Recently, several definition systems for AKI were proposed, incorporating both small changes of serum creatinine and urinary output reduction as diagnostic criteria. Novel biomarkers are under investigation as fast and accurate predictors of AKI. Several special considerations re...
متن کاملPerioperative acute kidney injury
Acute kidney injury (AKI) is a serious complication in the perioperative period, and is consistently associated with increased rates of mortality and morbidity. Two major consensus definitions have been developed in the last decade that allow for easier comparison of trial evidence. Risk factors have been identified in both cardiac and general surgery and there is an evolving role for novel bio...
متن کاملHaemoglobin, oxygen carriers and perioperative organ perfusion.
Under normal conditions, only 20-30% of the delivered oxygen is metabolised. In normovolaemic anaemia, the organism reacts with increases in cardiac output and oxygen extraction. Once these mechanisms are exceeded, allogeneic blood transfusions may be administered. However, such transfusions are associated with serious adverse effects and alternatives such as artificial oxygen carriers are bein...
متن کاملTargeting purinergic signaling for perioperative organ protection.
1001 May 2013 A D VA N C E M E N T S in the field of anesthesia have led to significant improvements in our monitoring capabilities, safer anesthetic drugs, and improved pain control. Despite this remarkable progress, acute organ injury remains one of the leading causes for morbidity and mortality in surgical patients. Patients who require a major surgical intervention—such as cardiothoracic, v...
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ژورنال
عنوان ژورنال: Anesthesiology
سال: 2013
ISSN: 0003-3022
DOI: 10.1097/aln.0000000000000022